Cold Plasma Market Size, Share and Trends 2024 to 2034

Cold Plasma Market Size and Forecast 2024 to 2034

The global cold plasma market size is calculated at USD 2.87 billion in 2024 and is predicted to reach around USD 10.93 billion by 2034, expanding at a CAGR of 14.31% from 2024 to 2034. The increasing implementation of cold plasma into various chronic disease treatments is driving the growth of the market.

Cold Plasma Market Key Takeaways

• North America led the cold plasma market and contributed more than 41% of the market share in 2023.
• Asia Pacific is projected to grow at the fastest CAGR of 16.82% during the forecast period.
• By pressure, the atmospheric pressure cold plasma segment accounted for the highest market share of 66% in 2023. 
• By pressure, the low-pressure cold plasma segment is growing at a notable CAGR of 17.02% over the forecast period.
• By application, the wound healing application segment generated the largest market share of 32% in 2023.
• By application, the cancer treatment application segment is projected to grow at a solid CAGR of 17.02% during the predicted period.

U.S. Cold Plasma Market Size and Growth 2024 to 2034

The U.S. cold plasma market size is evaluated at USD 0.94 billion in 2024 and is projected to be worth around USD 3.65 billion by 2034, growing at a CAGR of 14.53% from 2024 to 2034.

North America dominated the cold plasma market in 2023. The growth of the market is attributed to the rising healthcare infrastructure and the integration of technologies in it. The rising industrial infrastructure and technological advancements in the industries are driving the growth of the market. Additionally, the rising chronic illness in the population and the expenditure on healthcare, sterilization, and treatment methods. Increasing cancer cases in the United States are driving the demand for cold plasma for the treatment of the disease. The rising availability of the leading healthcare technologies and medical firms is collectively accelerating the growth of the cold plasma market in the region.

• The latest estimation of the new invasive cancer cases in the United States is 1,958,310 as per sex and cancer type, which is equivalent to about 5370 cases each day.
• It is recorded that there were about 609,820 mortality by cancer in the United States in 2023, which is equivalent to 1670 deaths per day.

Asia Pacific expects the fastest growth in the market during the forecast period. The growth of the market is owing to the rising population and the increasing demand for industrial development in the countries and further technical advancement. The rising geriatric population is driving the demand for efficient treatment procedures, and the evaluation of healthcare technologies is collectively boosting the growth of the cold plasma market across the region.

• The estimated number of cancer patients in India was 1,461,427 in 2022, with lung cancer ranked highest in men and breast cancer in women. There is a 12.8% expected increase in cancer cases by 2025 as compared to 2020.

Market Overview

Cold plasma is a fully or partially ionized gas that can be used in a wide range of industrial applications. The cold plasma is also known as the non-equilibrium plasma. In it, the electrons are at higher temperatures, and neutron atoms are at lower temperatures. Cold plasma is used in different industrial sectors such as wastewater management, medical science, healthcare, agriculture, and others. 

How Can AI Impact the Cold Plasma Market?

The integration of artificial intelligence into medicine creates the latest opportunities in the early treatment and diagnosis of disease. The integration of AI significantly improves and revolutionizes the field of plasma medicine. The increasing adoption of cold atmospheric plasma in different medicines and treatments. The use of AI in plasma medicine improves efficiency by analyzing large amounts of data, predicting treatment results, and increasing treatment protocol with enhanced precision. 

• In September 2023, US Medical Innovations, LLC (USMI) and the Jerome Canady Research Institute for Advanced and Biological Technological Sciences (JCRI-ABTS) announced cutting-edge achievements in robotic and surgical technology.  The Canady Robotic AI Surgical System is a one-of-a-kind AI robotic system that delivers cold atmospheric plasma (CAP). 

Cold Plasma Market Growth Factors

• Industrial usage: Cold plasma is highly used by several leading end-use industries, and it is used in industrial processes, including plasma-assisted chemical vapor deposition (PACVD) and plasma etching.
• Rising demand from the healthcare industry: The rising demand for cold plasma from the healthcare industry for increasing patient treatment procedures and advanced technologies with non-invasive and safer medical processes is enhancing the demand from the cold plasma market.
• Associated benefits: Cold plasma provides several benefits in different sectors and applications, including its use in medicines, such as the treatment of various chronic diseases and types of wound healing. Further, it is used in food, material science, wastewater treatment, skin rejuvenation, micro-coating, and others that boost the demand for cold plasma.
• Rising environmental awareness: The rising concern about environmental pollution caused by the harmful chemicals that are used in industrial operations, which create adverse effects on the environmental health of living beings and drive the demand for eco-friendly alternatives to those chemicals, is accelerating the growth of the cold plasma market.

Market Scope

Market Dynamics

Driver

The increase in the use of cold plasma in various healthcare applications

The rising adoption of cold plasma in different healthcare applications owing to its benefits in treatment, including high precision and cost-effectiveness in treatment, is driving the growth of the cold plasma market. It is used in healthcare applications like wound healing and prevention of skin diseases; it is highly efficient in providing cost-efficient and accurate cancer treatment in oral and dental diseases, and it is effectively used in treating fungal nail infections and other types of infections. Additionally, the rising investment in innovations and the launch of drugs and treatment procedures for chronic disease treatment accelerate the growth of the market. 

• In June 2023, Adtec Healthcare Limited, the original subsidiary of the parent company Adtec Technology Japan, introduced Cold Plasma on wounds in clinical trials, which is the leading technology aiming to treat chronic and infected wounds having strong antibacterial properties with no side effects. 

Restraint

Cost of implementation

The cost of installing cold plasma technology in industries is high due to its advanced and complex equipment, and the increased consumption of gas makes it expensive in nature, which limits the expansion of the cold plasma market.  

Opportunity

Use of cold plasma in food processing

Cold plasma is an emerging technology that helps improve the overall efficiency of various industrial operations. It is a proven non-thermal technology that is broadly used in the agriculture and food processing industry and helps in improving safety and efficiency. The cold plasma technology in enzyme denaturation, microbial decontamination, pesticide degradation, polyphenols, food allergens, food packaging, and various other physiological processes involved in food processing. 

Pressure Insights

The atmospheric pressure cold plasma segment dominated the cold plasma market in 2023. The increasing adoption of atmospheric pressure cold plasma by several leading industries such as material science, food and medical industry, surface treatment, and agriculture industry. It is the most cost-efficient technology that can be generated at atmospheric pressure and low temperature using different techniques and gases. The atmospheric pressure cold plasma is highly used in the food industry for modifying and extracting food and nutrients and processing food waste. The implementation of the atmospheric pressure cold plasma in the agriculture industry helps increase the length of the root and germination rates. It is highly environment friendly. It helps in degrading pollutants and is used in water and air purification.

The low-pressure cold plasma segment is predicted to witness significant growth in the cold plasma market over the forecast period. The low-pressure cold plasma is a non-thermal plasma made by using an electromagnetic field with a low-pressure space and utilizing chemically active gases. The low-pressure cold plasma is used in different applications like the food industry, textile industry, material processing, and plastic industry. The low-pressure cold plasma is a highly environment-friendly, chemical-free, and cost-effective solution that is used in different end-use industries.

Application Insights

The wound healing application segment registered its dominance over the cold plasma market in 2023. Cold plasma is one of the latest technologies or processes used in wound healing. The cold plasma consists of the reactive oxygen and nitrogen species, which are controlled by several factors, including gas flow rate, composition, voltage, frequency, power, and exposure time; it can be used against the inactivation or destruction of bacterial infection and increase the wound healing process. The reactive species that are present in the cold plasma damages the intracellular components and cell membrane, which destroys bacterial cells. The cold plasma increases the process of wound healing by activating macrophages, neutrophils, endothelial cells, fibroblasts, and keratinocytes. Cold plasma maintains the initiating angiogenesis, tissue oxygenation, and collagen synthesis that promotes rapid wound healing.

The cancer treatment application segment is expected to grow at the fastest rate in the cold plasma market during the predicted period. The rising cases of different types of cancer worldwide cause the demand for efficient and cost-effective treatment for it. The integration of the cold atmospheric plasma in the cancer provides efficient treatment with better precision. The cold atmospheric plasma used the ionized gas to kill the cancer cells. It is one of the rapid and reliable treatments for cancer; its cost efficiency and no side effects on the healthy cells of the body make it one of the promising treatments for cancer patients. Cold atmospheric plasma is used in various cancer treatments, including glioblastoma, breast cancer, melanoma, cervical cancer, and prostate cancer.

Cold Plasma Market Companies

• US Medical Innovations
• Apyx Medical
• Adtec Healthcare Limited
• Bovie Medical Corporation
• Neoplas Med GmbH
• Europlasma NV
• P2i Ltd.
• terraplasma medical GmbH
• CINOGY System GmbH

Recent Developments

• In September 2024, Viromed Medical AG is acquiring shares in ActivCell Group AG, Switzerland, and increasing its product portfolio. The collaboration increases the treatment spectrum of its products with additional indications and drives the market launch in the European Union with its own product series of cold plasma. 
• In June 2022, Intertronics, an adhesives specialist, launched the Relyon Plasma Piezobrush PZ3-i to its product range, providing the life sciences and the medical industry that provides a new way for automating plasma surface treatment. 

Segments Covered in the Report

By Pressure

• Low-Pressure Cold Plasma
• Atmospheric Pressure Cold Plasma

By Application

• Wound Healing
• Blood Coagulation
• Dentistry
• Cancer Treatment
• Other Medical Applications

By Geography

• North America
• Asia Pacific
• Europe
• Latin America
• Middle East and Africa