U.S. mRNA Therapeutics Market Size, Share, and Trends 2024 to 2034

The U.S. mRNA therapeutics market size is accounted at USD 5.48 billion in 2025 and is forecasted to hit around USD 11.89 billion by 2034, representing a CAGR of 9.00% from 2025 to 2034. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

  • Last Updated : February 2025
  • Report Code : 3862
  • Category : Healthcare

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology (Premium Insights)

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID-19 Impact on U.S. mRNA Therapeutics Market 

5.1. COVID-19 Landscape: US mRNA Therapeutics Industry Impact

5.2. COVID-19  Impact Assessment for the Industry

5.3. COVID-19 Impact: Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. U.S. mRNA Therapeutics Market, By Type

8.1. U.S. mRNA Therapeutics Market, by Type

8.1.1 Therapeutic Vaccines

8.1.1.1. Market Revenue and Forecast

8.1.2. Prophylactic Vaccines

8.1.2.1. Market Revenue and Forecast

8.1.3. Therapeutic Drugs

8.1.3.1. Market Revenue and Forecast

Chapter 9. U.S. mRNA Therapeutics Market, By Application

9.1. U.S. mRNA Therapeutics Market, by Application

9.1.1. Respiratory Diseases

9.1.1.1. Market Revenue and Forecast

9.1.2. Oncology

9.1.2.1. Market Revenue and Forecast

9.1.3. Rare Genetic Diseases

9.1.3.1. Market Revenue and Forecast

9.1.4. Infectious Diseases

9.1.4.1. Market Revenue and Forecast

9.1.5. Others

9.1.5.1. Market Revenue and Forecast

Chapter 10. U.S. mRNA Therapeutics Market, By End-use 

10.1. U.S. mRNA Therapeutics Market, by End-use

10.1.1. Research Organizations

10.1.1.1. Market Revenue and Forecast

10.1.2. Hospitals & Clinics

10.1.2.1. Market Revenue and Forecast

10.1.3. Others

10.1.3.1. Market Revenue and Forecast

Chapter 11. U.S. mRNA Therapeutics Market, Trend Forecast

11.1. U.S.

11.1.1. Market Revenue and Forecast, by Type

11.1.2. Market Revenue and Forecast, by Application

11.1.3. Market Revenue and Forecast, by End-use

Chapter 12. Company Profiles

12.1. GSK plc.

12.1.1. Company Overview

12.1.2. Product Offerings

12.1.3. Financial Performance

12.1.4. Recent Initiatives

12.2. BioNTech SE

12.2.1. Company Overview

12.2.2. Product Offerings

12.2.3. Financial Performance

12.2.4. Recent Initiatives

12.3. CureVac N.V.

12.3.1. Company Overview

12.3.2. Product Offerings

12.3.3. Financial Performance

12.3.4. Recent Initiatives

12.4. Sangamo Therapeutics, Inc.

12.4.1. Company Overview

12.4.2. Product Offerings

12.4.3. Financial Performance

12.4.4. Recent Initiatives

12.5. Translate Bio, Inc.

12.5.1. Company Overview

12.5.2. Product Offerings

12.5.3. Financial Performance

12.5.4. Recent Initiatives

12.6. Moderna, Inc.

12.6.1. Company Overview

12.6.2. Product Offerings

12.6.3. Financial Performance

12.6.4. Recent Initiatives

12.7. Argos Therapeutics Inc.

12.7.1. Company Overview

12.7.2. Product Offerings

12.7.3. Financial Performance

12.7.4. Recent Initiatives

12.8. Arcturus Therapeutics

12.8.1. Company Overview

12.8.2. Product Offerings

12.8.3. Financial Performance

12.8.4. Recent Initiatives

12.9. AstraZeneca plc.

12.9.1. Company Overview

12.9.2. Product Offerings

12.9.3. Financial Performance

12.9.4. Recent Initiatives

12.10. Pfizer Inc.

12.10.1. Company Overview

12.10.2. Product Offerings

12.10.3. Financial Performance

12.10.4. Recent Initiatives

Chapter 13. Research Methodology

13.1. Primary Research

13.2. Secondary Research

13.3. Assumptions

Chapter 14. Appendix

14.1. About Us

14.2. Glossary of Terms

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Frequently Asked Questions

The U.S. mRNA therapeutics market size is expected to increase USD 11.89 billion by 2034 from USD 5.13 billion in 2024.

The U.S. mRNA therapeutics market will register growth rate of 9.00% between 2025 and 2034.

The major players operating in the U.S. mRNA therapeutics market are GSK plc., BioNTech SE, CureVac N.V., Sangamo Therapeutics, Inc., Translate Bio, Inc., Moderna, Inc., Argos Therapeutics Inc., Arcturus Therapeutics, AstraZeneca plc., Pfizer Inc., CRISPR Therapeutics AG and Others.

The driving factors of the U.S. mRNA therapeutics market are the developments in bioinformatics and synthetic biology and mRNA platform allows for relatively rapid development of therapeutics compared to traditional methods.

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