Mice Model Market Size, Share and Trends 2024 to 2034

Mice Model Market Size and Forecast 2024 to 2034

The global mice model market size is expected to be valued at USD 10.78 billion in 2024 and is anticipated to reach around USD 19.36 billion by 2034, expanding at a solid CAGR of 6.03% over the forecast period 2024 to 2034. The North America mice model market size reached USD 8.24 billion in 2023. The increasing gene editing tools advancements, increased humanized mice model demands, human and mice physiological similarities, increasing personalized medicine consumption in developed and developing countries, etc. contribute to the growth of the market.

Mice Model Market Key Takeaways

• North America dominated the mice model market with the largest market share of 81% in 2023.
• Asia Pacific is estimated to be the fastest-growing during the forecast period of 2024-2034.
• By mice, the inbred segment generated the highest market share of 29% in 2023.
• By mice, the outbred segment is anticipated to be the fastest-growing during the forecast period.
• By technology, the CRISPR segment captured more than 34% of market share in 2023.
• By technology, the microinjection segment is expected to be the fastest-growing during the forecast period.

U.S. Mice Model Market Size and Growth 2024 to 2034

The U.S. mice model market size was exhibited at USD 10.17 billion in 2023 and is projected to be worth around USD 19.36 billion by 2034, poised to grow at a CAGR of 6.03% from 2024 to 2034.

• In March 2024, Phenix Bio company, located in California, Kentucky, United States, led a pharmaceutical advancement with innovative mice models.

Asia Pacific is estimated to be the fastest-growing during the forecast period of 2024-2034. The rapidly expanding biomedical research in the region is driven by rising pharma and biotech industries, rising investment in healthcare infrastructure, and government funding. The increasing prevalence of chronic disorders is raising the demand for mouse models in drug discovery and disease modeling. The growing pharmaceutical sector is fueled by rising demand for innovative therapeutics and healthcare expenditures, which contribute to the growth of the mice model market.

• In January 2024, a mutant COVID-19 variant GX_P2V that may cause a 100% death rate in humanized mice experienced by Scientists in China.

Market Overview

The mice model market is the subgroup of the biotechnology industry that focuses on the use and development of laboratory mice for research purposes. Mice models are the most commonly used animal models for human disease studies and various other good purposes. Mice are biologically the same as humans, and they get various similar diseases for similar genetic reasons. Mice may be genetically influenced to mimic effectively any human condition or disease. The applications of mice models include research and development of different types of diseases, academics, production, quality control, and other applications.

Mice Model Market Growth Factors

• The mice model in scientific research benefits include these are used for in vivo studies of diseases, it plays an important role in studying complex physiological systems and drug discovery.
• Mice models provide a platform for identifying disease causing gene mutations and modifying genes which contribute to the growth of the mice model market.
• Mice models can genetically be engineered for specific purposes like specific gene mutations and hosting patient tumors.
• Mice have a short life period, enabling researchers to study aging processes and chronic diseases over a lifetime.

How Can AI Improve the Mice Model?

The use of AI (Artificial Intelligence) in improving mouse models helps the growth of the mouse model market. AI is used in MICE education classrooms to interact with the students with the help of the internet for learning and by using AI to find a certain business. To improve video texture, image domain transformation, and animation and make them resemble real videos, AI is helpful for the MICE education classroom. The use of AI can solve some very old problems in the drug development and discovery process.

• In May 2024, by using genetic engineering, robotics, and artificial intelligence (AI), the world’s first automated animal research lab was launched by Olden Labs.
• In August 2024, a computer vision-based method to continuously and accurately measure mouse body mass was launched by The Jackson Laboratory and offered a novel resource for researchers that helps to improve the quality of a high range of preclinical studies.

Market Scope

Market Dynamics

Driver

Rising gene editing tool advancements

The advancement of targeted gene editing tools has greatly enhanced site-directed mutagenesis and led to better mouse model generation like conditional expression models, gene tagging, knock in and knock out with increased precision and efficiency, and also shorter turnaround, which helps the mice model market growth. Gene editing's most inspiring application is in the field of cell or gene therapy. The benefits of gene editing tools include potential cures for genetic diseases, more accurate and faster diagnosis and treatment of genetic disorders, extending human lifespan, and defeating and tackling diseases.

Restraint

Downsides of mice models

The downsides of the use of mice models for human diseases include the fact that mice can not be suitable models for specific human diseases, which can hamper the growth of the mice model market. The network linking genes in disease is different in humans and mice. The different mice strains can respond differently to experimental treatments or develop diseases at different rates, which leads to variability in experimental results. Mice lack genetic diversity, which is found in the human population; therefore, results from mice models can not be completely applied to humans.

Opportunity

Collaborative networks expansion

The collaborative network, research, and consortia can facilitate collaborative research, knowledge exchange, and data sharing that are helpful in the mice model community, which helps the growth of the mice model market. Open access initiatives, public & private partnerships, and multi-institutional collaborations will improve scientific discoveries, address global health challenges, and promote pre-competitive research through coordinated efforts in translational medicine and preclinical research.

• In January 2024, a highly immunocompromised hairless mouse model for oncology and immunology research was launched by Huntingdon Life Sciences and Harlan Laboratories.

Mice Insights

The inbred segment dominated the mice model market in 2023. The benefits of the inbred mice model include the ability to model specific human diseases, reproducibility, well-defined genetics and characteristics, etc. Inbred mice strains are colonies produced by a minimum of 20 generations of brother-sister mating, resulting in animals that are genetically similar within every strain. In scientific research, these strains are used and contribute to definitive results. As compared to other animal models like rabbits or rats, mice models may be easily genetically operated and inbred mice shows genetic homogeneity.

• In February 2023, a mouse model to study mpox virulence was developed by NIH Scientists. Standard inbred laboratory mice are resistant to MPXV infection, and the absence of a small animal model of mpox made it hard to study how genetic differences contribute to observed differences in virulence.

The outbred segment is expected to be the fastest-growing in the mice model market during the forecast period. Outbred mice are bred specially to maximize genetic diversity and heterozygosity in the population. In an outbred stock theory, no two individuals are genetically identical because of rotational breeding schemes that purposely prevent inbreeding, which contributes to the mice model market. Outbred mice tend to be larger, heartier, and better breeders than inbred mice.

The outbred mice models have many benefits, including increased genetic diversity, which makes them suitable for studying drug exposures and disease genomics, higher reproductive performance, higher disease resistance, longer lifespan, hybrid vigor, etc. Outbred mice models are used for pseudopregnancy, surgical models, aging, efficacy and safety testing, and general multipurpose models, etc.

Technology Insights

The CRISPR segment dominated the mice model market in 2023. The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) has been used to generate genetically advanced mice models including somatic genome editing models, KI/KO germline models, and mice models for drug treatment. CRISPR is an effective tool for genome editing in mouse models that enables the direct delivery of reagents into mouse zygotes.

CRISPR is RNA-guided genome editing in combination with pronuclear microinjection, which provides simplicity and efficiency for creating genetically engineered mice. As compared to other technologies, the main benefits of Cas-mediated genome engineering/CRISPR are the effectivity of target genomic loci and ease of constructing, designing, and constructing many sgRNAs, suggesting the multiplexed genome editing possibility in mammals.

• In March 2024, to manufacture and distribute affordable CRISPR Box Kits for High School Science Labs launched by the ChristianaCare Gene Editing Institute in collaboration with leading school science supplier Carolina Biological Supply Company.

The microinjection segment is estimated to be the fastest-growing in the mice model market during the forecast period. Microinjection is commonly used in transgenic mice production, which contributes to the growth of the mice model market. It involves introducing of foreign DNA into fertilized eggs to create disease models and to study gene functions.

The pronuclear microinjection method is highly used for generating transgenic mice. Microinjection has many benefits, including injection of small structures with high regeneration potential, enhancement chance for integrative transformation, not limited by the technique, accurate delivery of volume and timing, no need for selection markers, unparalleled accuracy in the delivery of genetic materials, integration and effective transfer of desired genes into host cells genome, etc.

Mice Model Market Companies

• Trans Genic Inc.
• The Jackson Laboratory
• Taconic Biosciences, Inc.
• Sage Labs
• PolyGene
• Ozgene Pty Ltd
• Janvier Labs
• Inotiv
• Hera Biolabs
• Harbour Biomed
• genOway S.A.
• Envigo
• Cyagen Biosciences Inc.
• Charles River Laboratories International, Inc.
• Allentown LLC
• TransViragen Inc.
• Aragen Life Sciences
• Crescendo Biologics
• Creative Biolabs
• JOINN Laboratories Co., Ltd.
• Creative Animodel
• Applied StemCell
• Ingenious Targeting Laboratory
• Vivo Bio Tech Ltd.
• Marshall BioResources
• TransCure bioServies
• JSR Corporation

Recent Developments

• In September 2023, the RenMice Series was launched by Biocytogen Pharmaceuticals (Beijing) Co., Ltd. The new series includes a collection of independently developed TCR mice and fully human antibody mice with proprietary intellectual property.
• In November 2023, the breeding of Cc2d1a-knockout allele with C2dla-/V5-HA mice generated a mice line with severe insufficiency of about 92% reduction in coiled-coil and C2 domain-containing protein 1A (CC2D1A) expression to generate a compound heterozygous murine model of autism spectrum disorder (ASD).
• In August 2024, a new approach to drug discovery that may revolutionize how we understand and treat diseases was launched by researchers at The Jackson Laboratory (JAX).

Segments Covered in the Report

By Mice

• Inbred
• Outbred
• Knockout
• Hybrid
• Other Mice

By Technology

• CRISPR
• Microinjection
• Embryonic Stem Cell Injection
• Nuclear Transfer
• Other Technologies

By Geography

• North America
• Asia Pacific
• Europe
• Latin America
• Middle East & Africa