Beckman Coulter Life Sciences Unveils Industry-First Modular Spectral Flow Cytometry Solution

Published: 28 Mar 2025

Author: Precedence Research

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Beckman Coulter Life Sciences has announced the launch of the CytoFLEX mosaic Spectral Detection Module first modular solution in the spectral flow cytometry landscape. It improves fluorescence sensitivity and provides such a detailed analysis of cells that investigators had not previously imagined. It accepts configuration with CytoFLEX LX or S* Flow Cytometers for a convenient approach to spectral flow cytometry. Unlike traditional methods using peak emission from fluorophores, spectral flow cytometry captures the entire emission of all lasers to characterize cells and understand their responses in a precise manner essential tool for immunological and disease research.

Key Features and Technological Advancements

Amazingly, the CytoFLEX mosaic Spectral Detection Module provides unmatched fluorescence sensitivity for multicolor experiments: it detects nanoparticles as small as 80 nm. Up to 10 autofluorescence channels combined with the two advanced and efficient unmixing algorithms are meant to provide a better understanding of immune cell subsets. This module seamlessly transfers conventional flow cytometry with spectral flow, thus lowering costs while improving the continuity of experiments. It is powered by the CytExpert analytical software for spectral analysis and thus streamlines the end-to-end workings from sample preparations to data analysis in workflow processes.

Such revolutionizing technology in spectral flow cytometry enables one to carry out an in-depth understanding of the multifaceted biological systems and disease through photon emission. The very basis of the CytoFLEX system portrays the simplicity of operation along with immensely powerful and sensitive acquisition, thereby enabling researchers to work between conventional and advanced spectral detection systems without having to invest in the instruments separately.

Practical Applications and Research Benefits

The new CytoFLEX mosaic Spectral Detection Module will change the face of Jsem research within immunology, cancer biology, and microbiology. It enables simultaneous multi-parameter analysis, allowing a much deeper understanding of cellular functions and the mechanisms of disease. The autofluor settings of the module are very flexible, especially while dealing with very complex samples such as human tissue and populations of microorganisms.

It adds sustainability and cost-effectiveness, as there is no need for spectral plus conventional cytometry instruments since all the same are incorporated, allowing money to be saved while improving the cost and accuracy of the whole experiments.

Global Availability and Product Configurations

Beckman Coulter Life Sciences has released the CytoFLEX mosaic Spectral Detection Module in two configurations: CytoFLEX mosaic 88 for the CytoFLEX LX Flow Cytometer and CytoFLEX mosaic 63 for the 4-laser CytoFLEX S Flow Cytometer. The module offers the potential for unparalleled cellular analytical capabilities, combining user-friendly design with powerful spectral detection technology; with its versatile nature, precision, and sustainability, this module revolutionizes immunology, oncology, and biomedical research with greater insights into complex biological processes while speeding up scientific discoveries.