Next-Generation Mass Spectrometer Market Size, Share and Trends 2025 to 2034

The global next-generation mass spectrometer market size is accounted at USD 2.37 billion in 2025 and is forecasted to hit around USD 4.43 billion by 2034, representing a CAGR of 7.22% from 2025 to 2034. The North America market size was estimated at USD 770 million in 2024 and is expanding at a CAGR of 7.38% during the forecast period. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

  • Last Updated : 05 Feb 2025
  • Report Code : 5530
  • Category : Healthcare

Next-Generation Mass Spectrometer Market Size and Forecast 2025 to 2034

The global next-generation mass spectrometer market size was calculated at USD 2.21 billion in 2024 and is predicted to increase from USD 2.37 billion in 2025 to approximately USD 4.43 billion by 2034, expanding at a CAGR of 7.22% from 2025 to 2034. The next-generation mass spectrometers experience rapid growth due to technological innovation, rising healthcare and pharmaceutical needs, environmental monitoring, government investments, and miniaturization for field applications.

Next-Generation Mass Spectrometer Market Size 2025 to 2034

Next-Generation Mass Spectrometer Market Key Takeaways

  • North America led the next-generation mass spectrometer market with the highest share of 35% in 2024.
  • Asia Pacific is anticipated to witness the fastest growth in the market during the forecasted years.
  • By type, the hybrid segment has generated a significant share of the market in 2024.
  • By type, the single mass spectrometer segment is projected to witness the fastest growth during the forecast period.
  • By application, the biotechnology segment noted the largest market share in 2024.
  • By application, the pharmaceutical segment is estimated to witness the fastest growth during the forecast period.
  • By end user, the hospitals segment noted the largest market share in 2024.
  • By end user, the research centers segment is estimated to witness the fastest growth in the forecast period.

Artificial Intelligence (AI) Integration in the Next-Generation Mass Spectrometer Market

The application of artificial intelligence, together with machine learning technologies, is revolutionizing the next-generation mass spectrometer market by replacing manual data processing while identifying concealed patterns in large datasets. AI-powered systems enhance the methods used in proteomics and metabolomics by delivering more precise results combined with better effectiveness levels. The worldwide market gains a substantial opportunity from integrating automation and AI with mass spectrometry. Modern laboratories benefit from automated processes that optimize sample analytics and boost laboratory test speed and efficiency rates.

  • In June 2024, SCIEX (a subsidiary of Danaher Corporation) revealed a partnership aimed at creating artificial intelligence quantitation (AI quant) software for analyzing data from the ZenoTOF 7600 and SCIEX 7500+ mass spectrometers.

U.S. Next-Generation Mass Spectrometer Market Size and Growth 2025 to 2034

The U.S. next-generation mass spectrometer market size was exhibited at USD 580 million in 2024 and is projected to be worth around USD 1,190 million by 2034, growing at a CAGR of 7.45% from 2025 to 2034.

U.S. Next-Generation Mass Spectrometer Market Size 2025 to 2034

North America accounted for the largest next-generation mass spectrometer market share in 2024. The expansion of the market in the area is propelled by the presence of key players and advanced industrial sectors. Moreover, the utilization of advanced and portable mass spectrometers boosts market growth. The regional market is led by the United States, with Canada and Mexico. The existence of leading pharmaceutical and biotechnology firms, paired with sophisticated research facilities and robust government support for scientific inquiry, has greatly enhanced market expansion in North America.

The growing emphasis on personalized medicine and clinical diagnostics has heightened the demand for mass spectrometry technologies. The ongoing integration of cutting-edge technologies, along with increasing uses in clinical diagnostics, proteomics, and metabolomics studies, keeps propelling market growth in these nations.

Market Overview

Mass spectrometers of the next generation use modern technological approaches to analyze compound structures. The next-generation mass spectrometer market enables scientists to discover new compounds by identifying molecular structures and recognizing substances. Complete scan analysis becomes available with optimized mass spectrometry performance, which synergistically results in better quantification capabilities and retroactive data interpretation. Next-generation mass spectrometers receive continuous enhancements through innovative software tools, which significantly accelerate their resolution performance capabilities.

The next-generation mass spectrometer market experiences growth through technological developments combined with increased pharmaceutical research, growth in biotechnology activities, and enhanced government and private spending. The developed testing approaches enable mass spectrometry studies across multiple elements in complicated samples by enhancing the resolution power for component detection. The market has grown substantially because of advanced mass spectrometer implementation. The ongoing growth relies heavily on expanded investment in mass spectrometry research.

Next-Generation Mass Spectrometer Market Growth Factors

  • Technological advancements: The development of next-generation mass spectrometers is advanced because modern technology focuses on high-resolution detectors and sensitive ion sources, which produce accurate and efficient analytical results for various applications.
  • Government investments: Government research support programs that target proteomics genomics and environmental sciences help next-gen mass spectrometers flourish through both funding for innovation and implementation of these testing methods.
  • Rising demand in healthcare: The increasing need for precision medicine alongside biomarker research drives the next-gen mass spectrometer market because these instruments provide better sensitivity and high specificity for drug development and medical diagnosis at precise levels.
  • Pharmaceutical industry growth: Next-generation mass spectrometers drive pharmaceutical industry expansion because they provide essential capabilities needed for screening and quality control during drug development procedures.

Market Scope

Report Coverage Details
Market Size by 2034 USD 704.23 Billion
Market Size by 2025 USD 351.71 Billion
Market Size in 2024 USD 325.59 Billion
Market Growth Rate from 2025 to 2034 CAGR of 8.02%
Dominated Region North America
Fastest Growing Market Asia Pacific
Base Year 2024
Forecast Period 2025 to 2034
Segments Covered Type, Application, End-user, and Regions
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa

Market Dynamics

Driver

Rising adoption in clinical diagnostics

The enhanced use of next-generation mass spectrometer market technologies in clinical diagnostics occurs because it measures complex biological specimens that help develop personalized treatments and better identify diseases. Mass spectrometry functions in proteomic analysis to both determine and measure proteins linked with diseases like cancer. The system tracks diabetes and neurodegenerative disorder metabolic shifts in metabolomics research. 

The identification of disease-related molecules using mass spectrometry enables medical professionals to discover biomarkers that enhance early disease diagnosis. With the next-generation mass spectrometer market technology, medical practitioners can obtain improved treatment personalization by developing therapies that match the distinct biological characteristics of individual patients. Researchers can use the analysis of breath, urine, and saliva samples to develop non-invasive diagnostic methods that improve both patient comfort and treatment compliance.

Restraint

High-cost

Mass spectrometry instruments, with their services, have a negative impact on market development due to their expensive nature. The elevated financial pressure stems from both instrument operating prices and routine servicing fees for these devices. High expenses discourage facilities from implementing these sophisticated instruments, which reduces their accessibility to budget-sensitive organizations. The next-generation mass spectrometer market benefits various industries because of its increasing market demand, yet its premium costs potentially restrain market development and restrict the practical application of mass spectrometry in critical areas of study.

Opportunity

Miniaturization trends

A notable trend has developed in the miniaturization of mass spectrometry instruments, fueled by technological advancements that allow the development of portable analytical devices. This shift from conventional devices has aided the creation of more sophisticated miniaturized mass spectrometry systems for on-site evaluation. Miniaturization trends in the next-generation mass spectrometer market hav0065 created new possibilities for field analysis and broadened their range of uses. These compact systems, known as micro-electro-mechanical systems (MEMS) mass spectrometers, are gaining popularity in several sectors, such as scientific research, space organizations, and forensic labs. 

Type Insights

The hybrid segment has generated a significant share of the next-generation mass spectrometer market in 2024. Hybrid mass spectrometry provides excellent resolution and mass precision, enabling various operational modes to analyze intricate samples with high specificity. Developments in technology in this sector, coupled with a rising demand from the biopharmaceutical and biotechnology sectors, are fueling growth in this segment. Hybrid mass spectrometers are composed of a minimum of two distinct types of mass analyzers set up in a sequence from the ion source to the ion detector, facilitating enhanced performance by integrating multiple mass analyzer elements.

The single mass spectrometer segment is projected to witness the fastest growth during the forecast period. Single mass spectrometry maintains prominence in both standard analytical applications and specialized fields despite its basic nature since it delivers adequate analysis to meet these requirements. Academic research labs and quality assurance applications rely on this technology for its dependable performance, simple control systems, and reasonable cost structure. The market expands its diversity through segments that deliver customized solutions to address unique analytical needs while complementing hybrid mass spectrometric capabilities.

Application Insights

The biotechnology segment noted the largest next-generation mass spectrometer market share in 2024. This sector grows because advanced biochemical research relies increasingly on mass spectrometry for vital work in biopharmaceutical discovery and development. The rising utilization of mass spectrometry for analyzing compounds, including proteins, peptides, carbohydrates, oligonucleotides, natural products, and drug metabolites, drives faster market growth. The application of nano-flow liquid chromatography with mass spectrometry technology drives their usage across diverse biotechnology fields.

The pharmaceutical segment is estimated to witness the fastest growth during the forecast period. The mass spectrometer applications across pharmaceutical studies span drug identification activities and product characterization functions. Mass spectrometry excels in pharmaceutical applications since its analytical method identifies compounds while maintaining molecular integrity throughout the process without modification to the sample. This technique supports biomarker research and therapeutic drug-tracking operations alongside pharmacogenomics investigations, leading to advances in individualized treatment programs. Corporate and government financial support for pharmaceutical research, government regulatory standards for drug safety and development, and pharmaceutical industry sector growth.

End-user Insights

The hospitals segment noted the largest next-generation mass spectrometer market share in 2024. Several medical and clinical laboratories have started to integrate mass spectrometry into routine patient management for multiple applications, such as therapeutic drug monitoring, toxicology, and endocrinology. Mass spectrometers in medical facilities perform multiple clinical roles, including the analysis of respiratory gases, newborn screening, and cancer diagnosis. This analytical instrument is useful for examining various clinical conditions, such as diabetes and respiratory well-being.

The research centers segment is estimated to witness the fastest growth in the forecast period. A mass spectrometer is a device employed to recognize and examine materials by measuring the ratio of mass to charge of their ions. This enables scientists to accurately assess the chemical makeup of a sample. Research institutions frequently utilize mass spectrometers for a range of purposes, such as drug discovery, protein assessment, environmental surveillance, forensic analysis, clinical testing, and metabolic research. Leading research centers often possess specialized mass spectrometry facilities to identify and quantify particular molecules in a sample, thereby supporting various research domains.

Next-Generation Mass Spectrometer Market Companies

Next-Generation Mass Spectrometer Market Companies
  • Thermo Fisher Scientific, Inc. (U.S.)
  • Shimadzu Corporation (Japan)
  • Agilent Technologies, Inc. (U.S.)
  • Bruker Corp (U.S.)
  • Waters Corporation (U.S.)
  • Danaher Corporation (U.S.)
  • PerkinElmer, Inc.
  • Rigaku Corporation
  • JEOL Ltd. (Japan)
  • LECO Corporation
  • Hiden Analytical (England)
  • Hitachi Ltd. (Japan)
  • Kore Technology (UK)
  • Ametek. Inc. (U.S.)

Industry Leader Announcement

  • In December 2024, Roche introduced the Cobas Mass Spec solution, a mass spectrometry analyzer poised to revolutionize the realm of clinical diagnostics,” stated Matt Sause, CEO of Roche Diagnostics. 

Recent Developments

  • In October 2024, MOBILion Systems unveiled novel high-resolution mass spectrometry functionality, signaling a significant change in proteomics processes. The new technology significantly improves speed and sensitivity, enabling researchers to perform complex analyses faster and with greater precision.
  • In September 2024, PerkinElmer collaborated with Emphor DLAS to provide analytical laboratory solutions throughout the UAE and Qatar. The services will cover mass spectrometry, atomic spectroscopy, chromatography, thermal analysis, and additional methods. 
  • In June 2024, Shimadzu unveiled a new series of LC-MS triple quadrupole mass spectrometers aimed at improving reliability and analytical capabilities. The new systems feature enhanced gas flow and improved nebulizer alignment, leading to increased sensitivity, accuracy, and reliability across different applications. 
  • In June 2023, Thermo Fisher Scientific Inc. introduced its Thermo Scientific Orbitrap Astral mass spectrometer, designed to identify new clinical biomarkers and develop new treatments for cardiovascular disease and cancer.

Segments Covered in the Report

By Type 

  • Hybrid 
  • Single Mass Spectrometer

By Application 

  • Pharmaceuticals
  • Biotechnology
  • Medical Research
  • Food and Beverage Testing

By End-User

  • Hospitals
  • Research Centers
  • Diagnostic Laboratories

By Geography

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

For questions or customization requests, please reach out to us at sales@precedenceresearch.com

Frequently Asked Questions

The global next-generation mass spectrometer market size is expected to grow from USD 2.21 billion in 2024 to USD 4.43 billion by 2034.

The next-generation mass spectrometer market is anticipated to grow at a CAGR of 7.22% between 2025 and 2034.

The major players operating in the next-generation mass spectrometer market are Thermo Fisher Scientific, Inc. (U.S.), Shimadzu Corporation (Japan), Agilent Technologies, Inc. (U.S.), Bruker Corp (U.S.), Waters Corporation (U.S.), Danaher Corporation (U.S.), PerkinElmer, Inc., Rigaku Corporation, JEOL Ltd. (Japan), LECO Corporation, Hiden Analytical (England), Hitachi Ltd. (Japan), Kore Technology (UK), Ametek. Inc. (U.S.), and Others.

The driving factors of the next-generation mass spectrometer market are the rising healthcare and pharmaceutical needs, environmental monitoring, government investments, and miniaturization for field applications.

North America region will lead the global next-generation mass spectrometer market during the forecast period 2025 to 2034.

Ask For Sample

No cookie-cutter, only authentic analysis – take the 1st step to become a Precedence Research client

Meet the Team

Deepa Pandey, one of our esteemed authors, plays a crucial role in shaping the high-quality content that defines our research reports. Deepa holds a Master's in Pharmacy with a specialization in Pharmaceutical Quality Assurance, equipping her with an in-depth understanding of the healthcare industry's regulatory, quality, and operational nuances. With 2+ years of experience in market research, Deepa has made

Learn more about Deepa Pandey

With over 14 years of experience, Aditi is the powerhouse responsible for reviewing every piece of data and content that passes through our research pipeline. She is not just an expert—she’s the linchpin that ensures the accuracy, relevance, and clarity of the insights we deliver. Aditi’s broad expertise spans multiple sectors, with a keen focus on ICT, automotive, and various other cross-domain industries.

Learn more about Aditi Shivarkar

Related Reports