Osteoarthritis Therapeutics Market Size, Share, and Trends 2024 to 2034

The global osteoarthritis therapeutics market size accounted for USD 9.91 billion in 2024, grew to USD 10.84 billion in 2025, and is expected to be worth around USD 24.34 billion by 2034, poised to grow at a CAGR of 9.4% between 2024 and 2034.

  • Last Updated : November 2024
  • Report Code : 2625
  • Category : Healthcare

Osteoarthritis Therapeutics Market Size and Forecast 2024 to 2034

The global osteoarthritis therapeutics market size is expected to be valued at USD 9.91 billion in 2024 and is anticipated to reach around USD 24.34 billion by 2034, expanding at a CAGR of 9.4% over the forecast period from 2024 to 2034.

Osteoarthritis Therapeutics Market Size 2024 to 2034

Osteoarthritis Therapeutics Market Key Takeaways

  • In 2023, Europe held the biggest market share of around 47% for degenerative joint disease activities. 
  • Asia-Pacific is predicted to have a CAGR of 8.7% between 2024 to 2034.
  • By distribution channel, the hospital pharmacies segment accounted for 38% of revenue share in 2023, according to research.
  • Based on anatomy, the knee osteoarthritis segment accounted for 44% of revenue share in 2023.
  • By drugs, the market was dominated by non-steroidal anti-inflammatory medications (NSAIDs) in 2023 with a revenue share of 39%.

Europe Osteoarthritis Therapeutics Market Size and Growth 2024 to 2034

The Europe osteoarthritis therapeutics market size is exhibited at USD 23.37 billion in 2024 and is projected to be worth around USD 59.83 billion by 2034, growing at a CAGR of 9.86% from 2024 to 2034.

Europe Osteoarthritis Therapeutics Market Size 2024 to 2034

Europe was the highest revenue holder in 2023. The market for osteoarthritis treatments was dominated by Europe. The large share of this particular market can be explained by the increasing pervasiveness of rheumatoid arthritis, the increasing geriatric population, as well as increasing obesity rates across several European countries, as well as the increasing amount of injuries sustained in sports as well as collisions on the street due to the presence of main players, accessibility of sophisticated scientific research for developing drugs, and rise in the number of arthritic approvals.

Osteoarthritis Therapeutics Market Share, By Region, 2023 (%)

However, because of factors like rising rates of osteoarthritis, growth in the number of women in the population, an expansion in healthcare spending, and a lack of physical activity, Asia-Pacific is predicted to have a CAGR of 8.7% between 2023 to 2032. Because it is the region of the world market with the quickest growth, Asia-Pacific also contributes to the growth. Large patient populations, supportive government regulations, and rising healthcare costs all contribute to this country's economic development.

Market Overview

The most prevalent type of osteoarthritis, arthritis, affects millions of individuals globally. When the required to prevent that cushioning of the bones at their ends gradually deteriorates, it happens. Though arthritis can harm any joint, it most frequently affects the hips, hands, knees, and spine joints.

A recent development in the realm of treating OA may give people who experience associated pain sensations a better joint range of motion. Chondroitin sulfate is discovered to dramatically lessen discomfort and increase hand movement in those with osteoarthritis. Two objectives of arthritis therapy are pain alleviation and improved functional status. To get the best results, patients must receive both pharmacologic and non-pharmacologic care.

Osteoarthritis Therapeutics Market Growth Factors

The osteoarthritis treatment market is anticipated to expand as the senior population rises. The most prevalent arthritis type among older adults is osteoarthritis, which is also one of the main causes of physical impairment. The condition affects both males and females.  Osteoarthritis most frequently affects the hands, neck, lower back, and muscle mass joints such that hips, knees, and feet. 

Osteoarthritis does not damage the inner organs; it only affects the joints. As you age, osteoarthritis is much more probable to occur. Osteoarthritis can be brought on by carrying too much weight, having your joints aligned incorrectly, and overworking an already wounded joint.

The industry for osteoarthritis therapies is anticipated to grow as arthritis, including hip or knee osteoarthritis, becomes more common. Knee osteoarthritis is believed to be caused by the disintegration of joint structures as a consequence of mechanical stress and irritation, but the deep root causes of cancer's high incidence are unclear and poorly understood, making it difficult to avoid and cure. 

However, it's largely believed that two current public health developments are the most significant. Due to a high BMI and the fact that knee OA is extra mutual as people age (BMI). Osteoporosis of the hip results in pain and stiffness. It can make ordinary actions challenging, such as getting up from a chair or leaning over there to tie your shoe.

The osteoarthritis treatment market is anticipated to be further stimulated by the increase in the need for cell-based studies for the disease. The advancement of osteoarthritis therapeutics based on stem cells is at a turning point. Researchers and clinicians can now look into the possibility of just using bone marrow to modify the advancement of osteoarthritis and epithelial designing to completely resurface an osteoarthritic joint exterior, going to prevent or postpone the requirement for total hip replacement

This is made possible by the body of literature on cell therapy solitude, chondrocyte distinctions, and formwork design. An increased prevalence of arthritis (OA) among some of the aged is a result of the rise in the world's aging population. The most prevalent kind of joint illness in those over 65, is also linked to a higher mortality rate and a junior standard of living. Osteoarthritis (OA), among the most prevalent causes of discomfort and incapacity in the senior population, is the main factor driving the market.

The lubrication layer of the combined, tissue, is also the subject of numerous arthritis investigations that are now being conducted. That regenerate cartilage, skin cells have been given chemicals to promote proliferation are being employed. The discovery of new chances for the Osteoarthritis Treatment Market is consequently being aided by continuing study and growing federal funding.

Market Scope

Report Coverage Details
Market Size in 2024 USD 9.91 Billion
Market Size by 2034 USD 24.34 Billion
Growth Rate from 2024 to 2034 CAGR of 9.4%
Largest Market Europe
Base Year 2023
Forecast Period 2024 to 2034
Segments Covered By Drugs, By Anatomy, By Purchasing Pattern, By Distribution Channel and By Route of Administration
Regions Covered North America, Europe, Asia-Pacific, Latin America and Middle East & Africa

Market Dynamics

Key Market Drivers

Cumulative administration expenditure proceeding cell-based studies; prevalent usage of painkillers.

Osteoporosis discomfort is recurrently treated through oral, dental, and parenteral analgesics. The reception of painkillers for the disease is substantially owed to the accessibility of supervision and the fee of narcotic painkillers, even if choices like orthopedic splints are applied as a component of a harmless technique of giving discomfort. Oral ache medicines such as paracetamol as well as NSAIDs such as naproxen, opiates, ibuprofen, and duloxetine are amongst the numerous formulae of anesthetics used.

Additional kinds contain pertinent managers similar to NSAIDs and capsaicin, established on bury activities like glucocorticoids but also hyaluronic mordant, and dietary complements include chondroitin and glucosamine. Rendering to training, using these pills right away diminishes severe discomfort by 30.00%. Over the next ten years, it is estimated that an increasing number of people would use painkillers to treat the pain brought on by osteoarthritis, which will fuel market expansion over the research period.

Key Market Challenges

NSAID use in the treatment of osteoarthritis is connected with a potential for adverse cardiovascular risk.

Patients with osteoarthritis frequently use NSAIDS, both over-the-counter and on prescription. Over 60% of persons in the US who have osteoarthritis of the knees accept nonsteroidal anti-inflammatory drugs, depending on a Bioengineering Document from 2019. Correspondingly, in the US, 60.00% of all European knee degenerative joint disease affected role who acquired remedy medicines also attained nonsteroid anti-seditious drugs. 

The ingesting of NSAIDs upsurges the coincidental of emerging thoughtful heart sickness. Mutually cox-2-specific nonsteroidal anti-inflammatory drugs and non-selective nonsteroidal anti-inflammatory drugs improve users' danger of CVD.

Nonsteroidal anti-inflammatory drugs are accountable for further than 3 of the augmented cardiac danger related to degenerative joint disease, rendering education obtainable at the annual Information European Assembly of Rheumatology. Such hazards linked with NSAID use may discourage physicians from prescribing these drugs while prompting OTC NSAID users to seek out alternative medicines.

Key Market Opportunities

Osteoarthritis treatment on an individual basis

Modified OA medications have remained conceptualized, which represents a significant advancement in the analysis, treatment, and valuation of illness harshness in patient role with knee joint degenerative joint disease. Easy dimension, improvement healthier of sensitivity also specificity, and counting examination methods that are amicable and effortlessly legible by surgeons are critical appearances that take quantifiable charge for a modified treatment method for osteoarthritis.

The application of pointers to identify entities who are the furthermost perspective to counter to specific treatments might recover the beneficial retort areas and inferior the danger of revealing affected role to tablets is moreover improbable to be obliging or determination reason foremost lateral belongings. Using a mixture of distinct markers & relevant clinical traits on different ages in addition to gender might aid in further improving attempts to tailor RA treatment plans.

Drugs Insights

The non-steroidal anti-inflammatory medications (NSAIDs) segment has captured the largest revenue share in 2023, and this trend is anticipated to continue over the projected timeframe due to a rise in NSAID drug acceptance, the introduction of new products, as well as a rise in the number of prescriptions. 

Even so, the utilized in an assortment agent market is anticipated to expand significantly over the course of the forecast period due to rising osteoarthritis pervasiveness, advancements in R&D for the creation of new small oil droplet agents, and govt initiatives to encourage research in the healthcare industry.

In 2023, it is anticipated that the market for osteoarthritis therapies would be dominated by viscosupplementation products. The primary reason for the expansion of this market is the increasing prevalence of osteoarthritis of the knee. 

Anatomy Insights

The knee osteoarthritis segment has held the highest revenue share in 2023. The market is divided into hand, knee, hip, & small-joint osteoarthritis therapies based on anatomy. The market's biggest and fastest-growing category is therapies for osteoarthritis of the knee. The high prevalence of osteoarthritis of the knee is the main cause of this.

Distribution Channel Insights

The hospital pharmacies segment dominated the market in 2023 and accounted largest revenue share. Owing to the significant amount of patient’s role who were treated for arthritis in clinics and the wide assortment of osteoarthritis drugs obtainable through these pharmacists, pharmacy technicians held the highest market share in this segment in 2023. Due to government schemes for improving hospital pharmacies and an increase in osteoarthritis incidence. 

Nevertheless, due to improvements in health technologies and an increase in the demand for distant services, the internet pharmacy market is anticipated to have substantial growth during the projected timeframe.

Route of Administration Insights

The parental route is anticipated to hold the highest share in 2023. The injectable route held the largest share in 2022 and is anticipated to experience the fastest CAGR growth over the course of the forecast timeframe. Due to its straightforwardness of management and improved pharmacokinetics and pharmacodynamics, the intravenous route has been widely adopted for the delivery of osteoarthritis treatments, which has led to greater patient adherence.

Purchasing Pattern Insights

The industry for osteoarthritis therapies had the biggest proportion in 2023, according to prescribed pharmaceuticals. Because the majority of corticosteroid & visco-supplementation treatments for arthritis are only accessible with a prescription in 2023, the market category for prescribed medications held a bigger share in 2023.

Osteoarthritis Therapeutics Market Companies

  • Abbott Laboratories
  • ABIOGEN PHARMA S.p.A
  • Ampio Pharmaceuticals Inc.
  • Anika Therapeutics Inc.
  • Bayer Aktiengesellschaft
  • Bioventus
  • Eli Lilly and Company.
  • Ferring B.V.
  • Flexion Therapeutics, Inc.
  • GlaxoSmithKline Plc. 
  • Horizon Therapeutics plc.
  • Johnson & Johnson Inc.
  • Medivir
  • Merck Sharp & Dohme Corp.
  • Novartis AG
  • OrthogenRx, Inc.
  • Pacira Pharmaceuticals, Inc
  • Pfizer, Inc.
  • PHARMED LTD.
  • Regeneron
  • Sanofi S.A
  • TissueGene Inc.
  • Zimmer Biomet Holding

Recent Developments

  • GlaxoSmithKline Pic (UK) introduced Voltaren in the US in 2020.
  • Ireland's Horizon Therapeutics Pic increased its footprint in the US in 2020.
  • A 2019 agreement between Kitov Pharma Ltd. (Israel) and Coeptis Pharmaceuticals has aided in the effective commercialization and distribution of Content.
  • In Dubai, United Arab Emirates, Atnahs opened a retail location in 2016.
  • In 2017, the FDA approved ZILRETTA from Flexion Therapeutics, Inc. (US).

Segments Covered in the Report

By Drugs

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)
    • Naproxen
    • Aspirin
    • Diclofenac
    • Ibuprofen
  • Viscosupplementation agents
  • Corticosteroids
  • Hyaluronic Acid Injection
  • Analgesics
    • Duloxetine
    • Acetaminophen

By Anatomy

  • Ankle Osteoarthritis
  • Hip Osteoarthritis
  • Knee Osteoarthritis
  • Shoulder Osteoarthritis
  • Others

By Purchasing Pattern

  • Prescription Drugs 
  • Over-the-counter Drugs

By Distribution Channel

  • Hospital Pharmacies
  • Hypermarket & Supermarket
  • Online Pharmacies
  • Retail Pharmacies
  • Others

By Route of Administration 

  • Parenteral Route 
  • Topical Route
  • Oral Route

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • The Middle East and Africa

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Frequently Asked Questions

The global osteoarthritis therapeutics market size was accounted at USD 9.91 billion in 2024 and it is expected to reach around USD 24.34 billion by 2034.

The global osteoarthritis therapeutics market is poised to grow at a CAGR of 9.4% from 2024 to 2034.

The major players operating in the osteoarthritis therapeutics market are Abbott Laboratories, ABIOGEN PHARMA S.p.A, Ampio Pharmaceuticals Inc., Anika Therapeutics Inc., , Bayer Aktiengesellschaft, Bioventus, Eli Lilly and Company., Ferring B.V., Flexion Therapeutics Inc., GlaxoSmithKline Plc., Horizon Therapeutics plc., Johnson & Johnson Inc., Medivir, Merck Sharp & Dohme Corp., Novartis AG, OrthogenRx, Inc., Pacira Pharmaceuticals, Inc, Pfizer, Inc., PHARMED LTD., Regeneron and Others.

Prevalent usage of painkillers is the primary driving factor of the osteoarthritis therapeutics market.

Europe region will lead the global osteoarthritis therapeutics market during the forecast period 2024 to 2034.

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Meet the Team

Sanket Gokhale is one of the key authors contributing to the high-quality, actionable insights that define our market research reports. Sanket holds an MBA with a specialization in Healthcare Management, coupled with a Bachelor’s degree in Pharmacy. With over 5 years of experience in market research, Sanket has cultivated a deep understanding of the healthcare sector, from pharmaceutical innovations to healthcare

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With over 14 years of experience, Aditi is the powerhouse responsible for reviewing every piece of data and content that passes through our research pipeline. She is not just an expert—she’s the linchpin that ensures the accuracy, relevance, and clarity of the insights we deliver. Aditi’s broad expertise spans multiple sectors, with a keen focus on ICT, automotive, and various other cross-domain industries.

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