The global custom antibody market size was USD 175.70 million in 2023, calculated at USD 192.80 million in 2024 and is expected to reach around USD 444.66 million by 2033, expanding at a CAGR of 9.73% from 2024 to 2033. Custom antibodies provide long-term protection against toxins, pathogens, allergens, and infections. These antibodies are used to treat specific health problems like rheumatoid arthritis, heart disease, cancer, and more, which help the growth of the market.
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The U.S. custom antibody market size was exhibited at USD 60.62 million in 2023 and is projected to be worth around USD 156.11 million by 2033, poised to grow at a CAGR of 9.92% from 2024 to 2033.
North America dominated the custom antibody market in 2023. Increasing investment in the field of drug discovery and development helps to the growth of the market in the North American region. The need for new targeted therapies contributes to the growth of the market. In the United States and Canada, large-scale genomics and cancer research programs are conducted.
Asia Pacific is estimated to be the fastest-growing during the forecast period of 2024-2033. India and China are the leading countries for the growth of the custom antibody market in the Asia Pacific region.
The custom antibody market is a rapidly evolving sector within biotechnology, characterized by significant advancements and a growing emphasis on personalized medicine. Custom antibodies are precisely engineered antibodies designed to target specific antigens and play a significant role in therapeutics, diagnostics applications, and research, which helps the growth of the market. Custom antibodies offer many benefits, including versatility and high specificity, to ensure accurate and reliable results.
Custom antibodies are important because they are therapeutics, non-commercially available polyclonal and monoclonal antibodies, and they significantly manage and treat many illnesses, including infectious diseases and cancers. Researchers use their antigen-binding activities to carry drugs to the targeted areas. In diagnostics, clinical projects, and clinical, basic, and translational research applications, custom antibodies are used. These factors help to the growth of the market.
| Report Coverage | Details |
| Market Size by 2033 | USD 444.66 Million |
| Market Size in 2023 | USD 175.70 Million |
| Market Size in 2024 | USD 192.80 Million |
| Market Growth Rate from 2024 to 2033 | CAGR of 9.73% |
| Largest Market | North America |
| Base Year | 2023 |
| Forecast Period | 2024 to 2033 |
| Segments Covered | Type, Service, Source, Application, End-use, and Regions |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa |
Rising demand for custom antibodies
Custom antibodies play a significant role in therapeutics, diagnostics, and scientific research. Custom antibodies undergo quality control to ensure reliability and consistency in research experiments. Its high specificity and versatility help to the growth of the market. Increasing life-science research funding helps to boost research and development activities for customized treatment, diagnostics, and drug discovery. Rising investment in life-science research like drug development, proteomics, and genomics. This leads to increased demand for reliable and highly specific antibodies. These factors help the growth of the custom antibody market.
Industry and academia collaboration
Pharmaceutical or biotechnology industries and academic institutions are increasingly working together on custom antibodies. This collaboration brings together expertise for the antibodies development with industry infrastructure and resources to advance the field and stimulate innovation. These factors help the growth of the market.
Different disadvantages of custom antibodies
The disadvantages of custom antibodies include the fact that they require high-cost production because they require suitable conditions for manufacturing practices, expensive purification steps, and the need for significant mammalian cell cultures. Disadvantages of monoclonal antibodies include their low affinity, high development cost, and long time for production. Polyclonal antibody's disadvantages include difficulty in production, it needs high requirements to purify immunogens, and it produces background signals in certain applications. These factors can restrict the growth of the custom antibody market.
Research & development
Implementation of new technologies like recombinant DNA technology and phase display can help the growth of the market. The development of new technologies will help reduce costs. Companies increased their investment in simplifying operations and automation technologies that help to reduce the production cost of the custom antibody. The investment in research and development of custom antibodies helps to advance biomedical science and improve human health. These factors help to the growth of the custom antibody market.
The monoclonal antibodies segment dominated the market in 2023. In medicines, monoclonal antibodies have several applications, including helping to work faster with faster results, lower toxicity, and improved safety as compared to chemotherapy drugs, which help to improve well-being and patient survival and reduce adverse side effects. This is the more accurate treatment for certain diseases like cancers and rheumatoid arthritis than the other treatments that help to improve effectiveness. The benefits of using monoclonal antibodies are their strong binding affinity, selectivity, and specificity. Monoclonal antibody's high purity and reproducibility properties help in many applications. These factors help to the growth of the monoclonal antibodies segment and contribute to the growth of the custom antibody market.
The recombinant antibodies segment is expected to be the fastest-growing during the forecast period. Recombinant antibodies offer many advantages over traditional antibodies. These include recombinant antibodies that can provide reproducible results and long-term supply and can be produced in larger quantities. Recombinant antibodies can provide amenability, superior lot-to-lot consistency, and continuous supply to antibody engineering. Recombinant antibodies are highly specific and with greater sensitivity as compared to monoclonal antibodies. They are derived from DNA and do not require animal immunization, animal serum products, or animal pathogens in the production process. These factors help to the growth of the recombinant antibodies and contribute to the growth of the custom antibody market.
The antibody development segment dominated the custom antibody market in 2023. The antibody development allows researchers to study new proteins and unique molecules with specificity and precision, as well as post-translational modifications. Antibodies are the proteins produced by the immune system that help to protect against toxins, infections, and allergens. The importance of custom antibodies increased due to their crucial role in diagnostic assays, therapeutic interventions, and vaccine development. Due to their higher specificity and reproducibility, there are fewer adverse effects. These factors help to the growth of the antibody development segment and contribute to the market.
The rabbit segment dominated the market in 2023. Rabbits offer unique benefits over mice in the production of antibodies as they are capable of producing antibody structures and a large variety of B cells. The rabbit immune system may produce antibodies with 10-100 times higher affinity for the target antigen than monoclonal antibodies in mice. Rabbit source is an ideal option for monoclonal antibody development. They can identify human antigen epitopes, help to reduce background noise, high affinity, and increased specificity, suitable for immunohistochemistry, and help in the detection of post-translational modifications. These beneficial factors help the growth of the rabbit source segment and contribute to the growth of the custom antibody market.
The mice segment is estimated to be the fastest-growing during the forecast period. Laboratory mice provide a ready source of various high-specificity and high-affinity monoclonal antibodies. Transgenic mice are used to express human antibody gene sequences to develop low immunogenicity monoclonal antibodies for in vivo therapy. This technology is used by many pharmaceutical and biotechnology companies to develop new therapeutics for monoclonal antibodies. These factors help to the growth of the mice segment and contribute to the growth of the custom antibody market.
The infectious disease segment dominated the market in 2023. For viral infectious diseases, custom antibodies are highly used because they are appealing as potential prophylactics and therapeutics for viral infections due to characteristics of ability and specificity to improve their immune responses. Antibodies help the body to fight toxins or the microbes they produce. Antibodies recognize the antigens on the surface of microbes or toxins as being foreign. Antibodies trigger the immune system to fight infection. These factors help to the growth of the infectious disease segment and contribute to the growth of the custom antibody market.
The oncology segment is estimated to be the fastest-growing during the forecast period. In oncology, antibody treatment helps target tumor cells directly and promotes the induction of long-lasting anti-tumor immune responses. Antibodies work by coating cancer cells to detect more easily the targeted destruction by the immune system, triggering cell membrane destruction, blocking cell growth, and helping to prevent blood vessel growth, which is essential for tumor growth. The advantages of custom antibodies for oncology include targeted treatment without harming healthy cells, fewer side effects as compared to other cancer treatments, and boosting immune response to fight cancer. These factors help to the growth of the oncology application segment and contribute to the growth of the custom antibody market.
The academic research & institutes segment dominated the custom antibody market in 2023. In academic research & institutes, custom antibodies play an essential role in advancing antibody technology and improving their utility and reliability, especially in the fields of biomedical studies, molecular biology, and immunology. The advantages of custom antibodies for academic research & institutes are high specificity for particular antigens to ensure reliable and accurate results, versatility due to their applications in therapeutics, diagnostics, and research, and quality control measures reliability and consistency. It also helps in research for isolation, detection, precision, and specificity. These factors help to the growth of the academic research & institutes segment and contribute to the growth of the market.
The pharmaceutical & biotechnology companies segment is expected to be the fastest-growing during the forecast period. Custom antibodies play an important role in pharmaceutical & biotechnology companies, mainly for drug development and discovery. The high specificity and versatility properties of custom antibodies lead to many applications, including therapeutics, diagnostics, and research. Custom antibodies play an important role in personalized medicine by facilitating targeted therapy development modified to individual patient's needs, which makes them invaluable for personalized and more effective treatment options. These factors help the growth of the pharmaceutical & biotechnology companies segment and contribute to the growth of the custom antibody market.
Segments Covered in the Report
By Type
By Service
By Source
By Application
By End-use
By Geography
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